Compounds useful as inhibitors of ATR kinase

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专利权人:

Vertex Pharmaceuticals Incorporated

发明人:

Nadia Ahmad,Jean-Damien Charrier,Chris Davis,Gorka Etxebarria I Jardi,Damien Fraysse,Ronald Knegtel,Maninder Panesar,Francoise Pierard,Joanne Pinder,Pierre-Henri Storck,John Studley

申请号：

US16116559

公开号：

US10800781B2

申请日:

2018.08.29

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention； methods of treating of various diseases, disorders, and conditions using the compounds of this invention； processes for preparing the compounds of this invention； intermediates for the preparation of the compounds of this invention； and solid forms of the compounds of this invention.The compounds of this invention have formula I-1 or I-A:wherein the variables are as defined herein.

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中国工程科技知识中心

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http://www.ckcest.cn/home/