תרכובות 2 – אמינו – 6– פלורו –n – [ – פלורו– פירידין – 3 יל] פיראזולו (1 , 5 – a ) פירימידין – 3 – קארבוקס אמיד, צורות מוצקות שלהן, תכשירים המכילים אותן ושיטות להכנתן

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED

发明人:

申请号：

IL24602816

公开号：

IL246028A

申请日:

2016.06.05

申请国别(地区):

IL

年份:

2020

代理人:

摘要：

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention； methods of treating of various diseases, disorders, and conditions using the compounds of this invention； processes for preparing the compounds of this invention； intermediates for the preparation of the compounds of this invention； and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/