Jean-Damien Charrier,Christopher John Davis,Damien Fraysse,Gorka Etxebarria I Jardi,Simon Pegg,Francoise Pierard,Joanne Pinder,John Studley,Carl Zwicker,Tapan Sanghvi,Michael Waldo,Ales Medek,David Ma
申请号:
US14561368
公开号:
US10160760B2
申请日:
2014.12.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention.The compounds of this invention have formula I-A or I-B:wherein the variables are as defined herein.