The present invention relates to substituted imidazo[4, 5-c]quinoline derivatives, the compounds of formula (I), wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, processes for their preparation, pharmaceutical compositions comprising compounds of formula (I), and their use in the treatment of diseases or disorders mediated by one or more kinases, particularly proliferative diseases or disorders such as cancer. These compounds can also be used in the treatment of inflammatory diseases and angiogenesis related disorders.本發明關於取代的咪唑[4,5-c]喹啉衍生物（該分子式(I)化合物）、用於製備它們的製程、包含分子式(I)化合物的醫藥組合物以及它們在治療由一或更多的激酶所媒介之疾病或失調的用途，其中R1、R2、R3、R4、R5、R6以及R7是如同說明書中所定義，該疾病或失調特別是增殖性疾病或失調，例如癌症。這些化合物也可用於治療發炎性疾病以及血管新生相關失調。
