UNIWERSYTET W BIALYMSTOKU;BIOAPEX, S.R.O;UNIVERZITA PALACKEHO V OLOMOUCI
发明人:
MORZYCKI JACEK WITOLD,OKLESTKOVA JANA,STRNAD MIROSLAV,WOJTKIELEWICZ AGNIESZKA,HOFFMANNOVA LUCIE
申请号：
ZA201105443
公开号：
ZA201105443B
申请日:
2011.07.22
申请国别(地区):
ZA
年份:
2012
代理人:
摘要：
This invention relates to novel saponin compounds of formula II wherein MBz denotes p-methoxybenzoyl, and R is selected from the group comprising C6-10 aryl, C6-10 aryl-C1-4 alkyl-, C1-18 alkanoyl, C3-18 alkenyl, C6-10 aryl-C(O)-, C6-10 aryl-C1-4 alkyl-C(O)-, wherein each of the groups can optionally be substituted. These compounds possess a selective cytostatic activity, useful, e.g., in the treatment of proliferative diseases. The invention further relates to methods of preparation of the novel compounds and to a pharmaceutical composition containing these compounds.
