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Compound, process for preparing a compound, use of a compound, method for treating a disease or condition, pharmaceutical composition, process for preparing a pharmaceutical composition, product, and kit.
专利权人:
OXAGEN LIMITED
发明人:
RICHARD EDWARD ARMER,ERIC ROY PETTIPHER,MARK WHITTAKER,GRAHAM MICHAEL WYNNE,JULIA VILE,FRANK SCHROER
申请号:
BRPI0906786
公开号:
BRPI0906786A2
申请日:
2009.01.19
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Compounds of general formula (I) wherein W is chloro or fluoro; R1 is phenyl optionally substituted with one or more substituents selected from halo, -CN, -C1-C6 alkyl, -SOR3, -SO2R3, -SO2N(R2)2, -N(R2)2, -NR2C(O)R3, -CO2R2, -CONR2R3, -NO2, -OR2, -SR2, -O(CH2)pOR2, and -O(CH2)p-O-(CH2)qOR2 wherein each R2 is independently hydrogen, -C1-C6 alkyl, -C3-C8 cycloalkyl, aryl or heteroaryl; each R3 is independently, -C1-C6 alkyl, -C3-C8 cycloalkyl, aryl or heteroaryl; p and q are each independently an integer from 1 to 3; and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.
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