"compound, pharmaceutical composition, use of a composition, use of a compound, and process for the preparation of a compound"

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专利权人:

LIXTE BIOTECHNOLOGY; INC

发明人:

FRANCIS JOHNSON,JOHN S. KOVACH

申请号：

BRPI0816553

公开号：

BRPI0816553A2

申请日:

2008.10.01

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

This invention provides the compound having the structure wherein n is 1-10； X is C&mdash；R11 or N, wherein R11 is H, OH, SH, F, Cl, SO2R7, NO2, trifluoromethyl, methoxy, or CO&mdash；R7, wherein R7 is alkyl, alkenyl, alkynyl, C3-C8 cycloalkyl, or aryl； Z is R2 is H or NR3R4, wherein R3 and R4 are each independently H, C1-C6 alkyl, or C3-C8 cycloalkyl； R5 is OH or SH； and R6, R12, R13, and R14 are each independently H, OH, SH, F, Cl, SO2R15, NO2, trifluoromethyl, methoxy, or CO&mdash；R15 wherein R15 is alkyl, alkenyl, alkynyl, C3-C8 cycloalkyl, or aryl, or a salt of the compound, which is useful in the treatment of tumors.

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