PYRAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF

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专利权人:

SANOFI

发明人:

ABECASSIS, PIERRE-YVES,TABART, MICHEL,DESMAZEAU, PASCAL

申请号：

NZ59757810

公开号：

NZ597578A

申请日:

2010.07.02

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

597578 Provided are pyrazole derivative compounds of the formula (I), where X is chlorine or fluorine, including 4-{ 3-[3-(2-chloro-4-trifluoromethylphenyl)ureido]-5-fluorobenzylamino} -1H-pyrazole-3-carboxamide and 4-{ 3-[3-(2-fluoro-4-trifluoromethylphenyl)ureido]-5-fluorobenzylamino} -1H-pyrrazole-3-carboxamide. The compounds have anticancer activity. Also provided is a process for preparing the compounds and medicaments and pharmaceutical compositions comprising these compounds.

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