Parren, Paul,Beurskens, Frank,De Jong, Rob N.,Verploegen, Sandra,Labrijn, Aran Frank,Schuurman, Janine
申请号：
AU2018260863
公开号：
AU2018260863A1
申请日:
2018.11.07
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Described herein are polypeptides and related antibodies comprising a variant Fc domain. The variant Fc domain provide for stabilized Fc:Fc interactions when the polypeptide(s), antibody or antibodies are bound to its target, antigen or antigens on the surface of a cell, thus providing for improved complement-dependent cytotoxicity (CDC).
