AMINOQUINOLONES SPIROCYCLIQUES UTILISEES EN TANT QU'INHIBITEURS DE GSK-3

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专利权人:

KYORIN PHARMACEUTICAL CO., LTD.;ACTIVX BIOSCIENCES, INC.

发明人:

COCIORVA, OANA,FUKUDA, YASUMICHI,KOHNO, YASUSHI,LI, BEI,OKADA, KYOKO,NAKAMURA, AYAKO,NOMURA, MASAHIRO,SETO, SHIGEKI,SZARDENINGS, KATRIN,YUMOTO, KAZUHIRO

申请号：

CA2699152

公开号：

CA2699152C

申请日:

2008.09.12

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Provided herein arespirocyclic aminoquinolones of formulaI and compositions containing thecompounds. The compounds andcompositions provided herein are useful inthe prevention, amelioration or treatmentof GSK- 3 inhibitors mediated diseases.In Formula (I): X1 is O or NR8； A isbond or substituted or unsubstituted C1-C2alkylene, wherein the substituents whenpresent are selected from one to four Q2groups； where Q2 is alkyl or haloalkyl； pis 0 or 1； and q is an integer of 0 to 2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/