МУН Хон Сик (KR),ЙИ Хань Цзу (KR),ЧАЕ Еунь Хее (KR),ЧАЕ Сан Ми (KR),ШИНЬ Хье Вон (KR)
申请号：
RU2013102958/15
公开号：
RU2013102958A
申请日:
2011.07.08
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A pharmaceutical composition for the prevention or treatment of a disease selected from the group consisting of diabetic nephropathy, diabetic neuropathy, vascular complications of diabetes, hyperlipidemia, coronary heart disease and inflammation, containing a therapeutically effective amount of a compound selected from the group consisting of a compound of formula I, the following, a pharmaceutically acceptable salt, isomer, solvate or hydrate thereof, and combinations thereof； and a pharmaceutically acceptable carrier, wherein X is at least one substituent selected from the group consisting of hydrogen, straight or branched C1-C6 alkyl, F, Cl or Br-containing halogen, a straight or branched chain C1-C6 alkoxy, nitro and trifluoromethyl； X represents at least one substituent selected from the group consisting of hydrogen, a linear or branched C1-C6 alkyl, halogen, a linear or branched C1-C6 alkoxy, nitro, trifluoromethyl, and if X contains two or more than two substituents, then they are identical or different from each other, and form a ring together with an adjacent carbon atom； a Y represents hydrogen or methyl, or forms a carbonyl together with an adjacent carbon atom. 2. The pharmaceutical composition according to claim 1, wherein the compound is selected from the group consisting of 3- [4- (3,4-dimethoxyphenyl) piperazin-1-yl] -3-oxo-1-phenylpropyl ester of carbamic acid, 3- [4 - (3,4-dimethoxyphenyl) piperazin-1-yl] -1- (4-fluorophenyl) -3-oxopropyl ester of carbamic acid, 3- (4-benzo [1,3] dioxol-5-ylpiperazin-1- yl) -3-oxo-1-phenylpropyl ester of carbamic acid, 3- [4- (3,4-dimethoxyphenyl) -pipe hydrochloride1. Фармацевтическая композиция для предупреждения или лечения заболевания, выбранного из группы, состоящей из диабетической нефропатии, диабетической невропатии, сосудистых осложнений диабета, гиперлипидемии, ишемической болезни сердца и воспаления, содержащая терапевтически эффективное количество соединения, выбранного из группы, состоящей из соеди
