LE DIGUARHER, Thierry,CASARA, Patrick,STARCK, Jérôme-Benoît,HENLIN, Jean-Michel,DAVIDSON, James Edward Paul,MURRAY, James Brooke,GRAHAM, Christopher John,CHEN, I-Jen,GENESTE, Olivier,HICKMAN, John,DEP
申请号：
ES13704189
公开号：
ES2616679T3
申请日:
2013.01.23
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
Compound of formula (I): ** Formula ** where: - X and Y represent a carbon or nitrogen atom, it being understood that they cannot simultaneously represent two carbon atoms or two nitrogen atoms, - the Het part of the group represents an optionally substituted cycle, aromatic or not, formed by 5, 6 or 7 ring members, and which may contain, in addition to the nitrogen represented by X or Y, from one to three heteroatoms independently selected from oxygen, sulfur and nitrogen, it being understood that the nitrogen in question may be substituted with a group represented by a hydrogen atom, a linear or branched (C1-C6) alkyl group, or a -C (O) -O-Alk group, in which Alk is an alkyl group (C1-C6) linear or branched, - R1 and R2 independently represent each other, a hydrogen atom or a linear or branched (C1-C6) alkyl group, or R1 and R2, together with the nitrogen atom that carries them , form a heterocycloalkyl of 4 to 7 members of a N and which may contain, in addition to the nitrogen atom, another heteroatom selected from oxygen, sulfur, SO2 and NR, R representing a hydrogen atom, a linear or branched (C1-C6) alkyl group, a (C1-C6) alkylsulfonyl group ), a linear or branched (C1-C6) polyhaloalkyl group or a -C (O) -O-Alk group where Alk is a linear or branched (C1-C6) alkyl group, - R3 represents a (C1-C6) alkyl group ) linear or branched, alkenyl (C2-C6), alkynyl (C2-C6), cycloalkyl, cycloalkyl (C4-C10) linear or branched (C1-C6) alkyl, aryl or heteroaryl, - R4 represents an aryl, heteroaryl group, linear or branched cycloalkyl or (C1-C6) alkyl, - R5 represents a hydrogen or halogen atom, - Ra, Rb, Rc and Rd represent, independently of one another, a hydrogen atom, a halogen atom, an alkyl group (C1-C6) linear or branched, a linear or branched (C1-C6) alkoxy group, a hydroxy group, a linear or branched (C1-C6) polyhaloalkyl group or a tr group ifluoromethoxy, or the substituents of one of the couples (Ra, Rb), (Rb, Rc) or (Rc, Rd), together with the carbon atoms that c
