PAPADOPOULOS, NICHOLAS J.,MARTIN, JOEL H.,SMITH, ERIC,NOGUERA-TROISE, IRENE,THURSTON, GAVIN
申请号：
CA2672622
公开号：
CA2672622C
申请日:
2007.12.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDII4) and blocks hDII4 binding to a Notch receptor. The human anti- hDII4 antibody or antibody fragment binds hDII4 with an affinity of <；= 500 pM, as measured by surface plasmon resonance.
