Papadopoulos, Nicholas J.,Noguera-Troise, Irene,Smith, Eric,Martin, Joel H.,Thurston, Gavin
申请号:
AU2007334366
公开号:
AU2007334366B2
申请日:
2007.12.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDII4) and blocks hDII4 binding to a Notch receptor. The human anti- hDII4 antibody or antibody fragment binds hDII4 with an affinity of ≤ 500 pM, as measured by surface plasmon resonance.