ERIC SMITH,GAVIN THURSTON,IRENE NOGUERA-TROISE,JOEL H. MARTIN,NICHOLAS J. PAPADOPOULOS
申请号：
BRPI0720021
公开号：
BRPI0720021A2
申请日:
2007.12.14
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDII4) and blocks hDII4 binding to a Notch receptor. The human anti-hDII4 antibody or antibody fragment binds hDll4 with an affinity of ‰¤ 500 pM, as measured by surface plasmon resonance.
