PAPADOPOULOS, NICHOLAS J.,MARTIN, JOEL H.,SMITH, ERIC,NOGUERA-TROISE, IRENE,THURSTON, GAVIN
申请号：
PL07862940
公开号：
PL2115003T3
申请日:
2007.12.14
申请国别(地区):
PL
年份:
2012
代理人:
摘要：
An isolated human antibody or a fragment of a human antibody which specifically binds to human delta-like ligand 4 (hDII4) and blocks hDII4 binding to a Notch receptor. The human anti-hDII4 antibody or antibody fragment binds hDll4 with an affinity of ‰¤ 500 pM, as measured by surface plasmon resonance.
