Derivati 2-hidroksi-1-(4-((4-fenilfenil)karbonil)piperazin-1-il)etan-1-ona in povezane spojine, kot inhibitorji sintaze maščobne kisline (FASN) za zdravljenje raka
BAIR Kenneth W.,LANCIA David R. Jr.,LI Hongbin,LOCH James,LU Wei,MARTIN Matthew W.,MILLAN David S.,SCHILLER Shawn E.r.,TEBBE Mark J.
申请号：
SI201431348
公开号：
SI2968316T1
申请日:
2014.03.11
申请国别(地区):
SI
年份:
2019
代理人:
摘要：
The present invention relates to a list of specific 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (FAS or FASN) inhibitors for treating cancer and pharmacutical compositions thereof .An illustrative compound of the invention is shown below:
