KESTELEYN, BART RUDOLF ROMANIE,RABOISSON, PIERRE JEAN-MARIE,VAN DE VREKEN, WIM,CANARD, MAXIME FRANCIS JEAN-MARIE GHISLAIN
申请号：
AT06707683
公开号：
AT538121T
申请日:
2006.01.10
申请国别(地区):
AT
年份:
2012
代理人:
摘要：
HIV inhibitory compounds of formula: salts and stereoisomers thereof, wherein R1 and R2 are hydrogen or optionally substituted C1-10alkyl； R3 is n is 1, 2 or 3； R3a is nitro, cyano, amino, halo, hydroxy, C1-4alkyloxy, hydroxycarbonyl, aminocarbonyl, C 1-4alkyloxycarbonyl, mono- or di(C1-4alkyl)aminocarbonyl, C1-4alkylcarbonyl, methanimidamidyl, mono- or di(C1-4alkyl)methanimidamidyl, N-hydroxy-methanimidamidyl or Het； or R3 is a monocyclic or bicyclic aromatic heterocyclic ring system, wherein one, two, three or four ring members are nitrogen, oxygen and sulfur, and wherein the remaining ring members are carbon atoms； and wherein each of said heterocyclic ring systems may optionally be substituted； X is -NR7-, -O- or -S-； pharmaceutical compositions containing these compounds, methods for preparing these compounds and compositions.
