CHANG, ESTHER, H. H.,PIROLLO, KATHLEEN F. F.,凱瑟琳.,.皮羅洛,埃斯特.,.章,凱瑟琳.,.皮羅洛
申请号:
HK14101408.8
公开号:
HK1188147B
申请日:
2014.02.14
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
A method for preparing a stable cell-targeting complex comprising a ligand and a cationic liposome encapsulating a therapeutic or diagnostic agent comprises (a) combining the complex with a solution comprising a stabilizing amount of sucrose and (b) lyophilizing the resultant solution to obtain a lyophilized preparation; wherein, upon reconstitution, the preparation retains at least about 80% of its pre-lyophilization activity.