ATTENUATED LIVESTOCK VACCINES AGAINST PLEUROPNEUMONIA IN PIGS

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专利权人:

LABORATORIOS HIPRA; S.A.

发明人:

PINOL RIBAS, JAUME,BRU VIRGILI, SERGI,ESPUNA MASO, ENRIC,QUEROL MURILLO, ENRIQUE

申请号：

AT03779956

公开号：

AT543511T

申请日:

2003.11.17

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

The present invention provides a method for obtaining an immunogenic, non-haemolytic strain of Actinobacillus pleuropneumoniae which is modified, at least in a segment of the apxIA gene and optionally in a segment of the apxIIA gene that encodes a transmembrane domain of the Apx haemolytic and cytolytic exotoxins. It comprises also the strains, and the attenuated live vaccine porcine pleuorpneumonia obtained therewith.

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