PINOL RIBAS JAUME,BRU VIRGILI SERGI,ESPUNA MASO ENRIC,QUEROL MURILLO ENRIQUE,PIÑOL RIBAS JAUME,ESPUÑA MASO ENRIC
申请号：
PL37652703
公开号：
PL212312B1
申请日:
2003.11.17
申请国别(地区):
PL
年份:
2012
代理人:
摘要：
The present invention provides a method for obtaining an immunogenic, non-haemolytic strain of Actinobacillus pleuropneumoniae which is modified, at least in a segment of the apxIA gene and optionally in a segment of the apxIIA gene that encodes a transmembrane domain of the Apx haemolytic and cytolytic exotoxins. It comprises also the strains, and the attenuated live vaccine porcine pleuorpneumonia obtained therewith.
