VACCIN ATTENUE VIVANT CONTRE LA PLEUROPNEUMONIE DU PORC

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专利权人:

LABORATORIOS HIPRA; S.A.

发明人:

PINOL RIBAS, JAUME,BRU VIRGILI, SERGI,ESPUNA MASO, ENRIC,QUEROL MURILLO, ENRIQUE

申请号：

CA2505869

公开号：

CA2505869C

申请日:

2003.11.17

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The present invention provides a method for obtaining an immunogenic, nonhaemolytic strain of Actinobacillus pleuropneumoniae which is modified, atleast in a segment of the apxIA gene and optionally in a segment of the apxIIAgene that codes a transmembrane domain of the Apx haemolytic and cytolyticexotoxins. It comprises also the strains, and the attenuated live vaccineagainst porcine pleuropneumonia obtained therewith.

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