A nucleic acid encoding a chimeric protein, the chimeric protein including (i) at least one amino acid sequence having at least 50% sequence identity with any of the amino acid sequences selected from the group consisting of SEQ ID NOS: 1-5, and (ii) at least one amino acid sequence having at least 80% sequence identity with any of the amino acid sequences selected from the group consisting of SEQ ID NOS: 6-8. The chimeric protein includes at least one amino acid sequence of (i) and at least one amino acid sequence of (ii) that are from different Borrelia strains or species.
