MEIJI SEIKA PHARMA CO., LTD.;MICROBIAL CHEMISTRY RESEARCH FOUNDATION
发明人:
申请号：
ARP160102333
公开号：
AR105547A1
申请日:
2016.07.29
申请国别(地区):
AR
年份:
2017
代理人:
摘要：
Disclosed are a compound or a salt or solution acceptable to a drug thereof, a pharmaceutical ingredient thereof and a method thereof for the prevention or treatment of infectious diseases, and a method for the prevention or treatment of infectious diseases using these systems. This compound has antibacterial activity against bacteria, so Gram-positiveA as gram negative, it helps to prevent or treat infectious diseases caused by these bacteria. 1. Characteristic 1: compound with general formula (1) or its salts or soluble drugsR1 is hydrogen atom or hydroxyl group； R2 is hydrogen atom or amino group； R3 is hydrogen atom, halogen atom, hydroxyl group or amino group； r83088 is hydrogen atom, halogen atom, hydroxyl group or amino group； R1 and r830808 can form a double-layer link together； r830909 is a hydrogen atom, a hydroxyl group or an Amin group； r8310 is a hydrogen atom, a hydroxyl group or an Amin group； r8311 is a hydrogen atom, a hydroxyl group or an Amin group； r831222 is a hydrogen atom, a hydroxyl group or an Amin group； R8313 and r183044 are independent,One hydrogen atom, one c832131 asphalt group；an amino-C-alkyl group,a guanidino-C₁₋₆ alkyl group,1. Amino cycloquilo c83231 and 832727；an amino-C₃₋₇-C₁₋₆-C alquilo alkylan amidino group, an azetidino group optionally substituted with a C₁₋₆ alkyl group,A family of greecheros, a family of sarcocilo, a family of l-alanilo, a family of d-alanilo, a family of l-serilo, a family of d-serilo, a family of b-alanio, a family of l-isserie or a family of d-isserie； and a family of R-1 is a hydrogen atom, a hydroxyl group or a fluorine atom, except (I) family R1,R830808,R83099,R831222 and R1 are hydroxyl groups, R2,R3,R8310,R8311th,R83013 and r183044 are hydrogen atoms, (II) r83099；R831222 and R1 are hydroxyl groups, R1,R2,R3,R830808,R8310,R8311th,R8313 and R1 83044 are hydrogen atoms, (III) R1,R83099,R831222 and R1 are hydroxyl groups, R2,R3,R830808,R8310,R8311th,R8313 and R1 83044 are hydrogen atoms, (IV) R1,R830808
