CHARLES DAVID WEAVER,COLEEN M.NISWEDER,CRAIG W.LINDSELY,P.JEFFEY CONN,YIU-YIN CHEUNG
申请号:
BR112012010738
公开号:
BR112012010738A2
申请日:
2010.11.08
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
In one aspect, the invention relates to sulfone compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.