COLLEEN M. NISWENDER,COREY R. HOPKINS,CRAIG W. LINDSLEY,P. JEFFREY CONN,ROCCO D. GOGLIOTTI
申请号:
BR112012009576
公开号:
BR112012009576A2
申请日:
2010.10.22
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
Pyrazole compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.