Conn, P. Jeffrey,Lindsley, Craig W.,Hopkins, Corey R.,Weaver, Charles David,Niswender, Colleen M.,Cheung, Yiu-Yin
申请号:
AU2010314891
公开号:
AU2010314891A1
申请日:
2010.11.08
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
In one aspect, the invention relates to sulfone compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.