P. Jeffrey Conn,Craig W. Lindsley,Corey R. Hopkins,Charles David Weaver,Colleen M. Niswender,Yiu-Yin Cheung
申请号:
US13508535
公开号:
US20120245185A1
申请日:
2010.11.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
In one aspect, the invention relates to sulfone compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) synthetic methods for making the compounds pharmaceutical compositions comprising the compounds and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.