Georgette Castanedo,Bryan Chan,Matthew C. Lucas,Brian Safina,Daniel P. Sutherlin,Zachary Sweeney
申请号：
US13854635
公开号：
US08563540B2
申请日:
2013.04.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
