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HETEROCYCLIC COMPOUNDS AND METHODS OF USE
专利权人:
Stephen Price;Eileen Mary Seward;Daniel P. Sutherlin;Robert Heald;Brian Safina;Bohdan Waszkowycz;Pascal Pierre Alexandre Savy
发明人:
Robert Heald,Stephen Price,Brian Safina,Pascal Pierre Alexandre Savy,Eileen Mary Seward,Daniel P. Sutherlin,Bohdan Waszkowycz
申请号:
US13369016
公开号:
US20120202785A1
申请日:
2012.02.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
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