Jon H. Rasmussen;Palle H. Rasmussen;Wolfgang O. Wachs;Stefan Hansen;Jens Fomsgaard
发明人:
Jon H. Rasmussen,Palle H. Rasmussen,Wolfgang O. Wachs,Stefan Hansen,Jens Fomsgaard
申请号：
US12189925
公开号：
US08173770B2
申请日:
2008.08.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The peptides Ac-D-2Nal-D-4ClPhe-D-3Pal-OH and Boc-D-2Nal-D-4ClPhe-D-3Pal-OH are intermediates useful in the synthesis of LHRH analogs by coupling with suitable heptapeptides, in particular with the heptapeptides P1-Ser(P2)-MMeTry(P3)-D-Lys(Nic)-Leu-Lys(iPr,P4)-Pro-D-AlaNH2 and P1-Ser(P2)-NMeTry(P3)-D-Asn-Leu-Lys(iPr,P4)-Pro-D-AlaNH2.
