It refers to the compound (I) in the form of single vehicle, in which R1, x, Z1, l, N, ring a, ring B and ring C are described in this document. The most popular compounds are: (s) n - (4-methyl-5-oxo-5,6,7,8-tetrahydro-4h-pyrazole [1,5-a] [1,3] dibenzodiazo-6-il) - 4-phenol； 1-phenyl-n - (1-methyl-2-oxo-1,2,3,4,5,6-hexahydro-dibenzodiazo [1,5-a] [1,3] diphenyl-3-il) - 1h-3-trinitrotriamide. He also mentioned a pharmaceutical composer These compounds are protein inhibitors that interact with 1 (rip1) anion receptor and can be used to treat irritable bowel disorders, Crohn's disease and ulcerative colitis.SE REFIERE A COMPUESTOS DERIVADOS DE LACTAMAS BICICLICAS DE FORMULA (I) EN DONDE R1, X, Z1, L, n, EL ANILLO A, EL ANILLO B Y EL ANILLO C SON TAL COMO SE DESCRIBEN EN EL PRESENTE DOCUMENTO. SON COMPUESTOS PREFERIDOS: (S)-N-(4-METIL-5-OXO-5,6,7,8-TETRAHIDRO-4H-PIRAZOLO[1,5-a][1,3]DIAZEPIN-6-IL)-4-FENOXIPICOLINAMIDA； 1-BENCIL-N-(1-METIL-2-OXO-1,2,3,4,5,6-HEXAHIDROIMIDAZO[1,5-a][1,3]DIAZOCIN-3-IL)-1H-1,2,4-TRIAZOL-3-CARBOXAMIDA； ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE LA PROTEINA QUE INTERACTUA CON EL RECEPTOR 1 (RIP1) CINASA SIENDO UTILES EN EL TRATAMIENTO DE TRASTORNOS DEL INTESTINO IRRITABLE, ENFERMEDAD DE CROHN, COLITIS ULCEROSA
