MAHER, JOHN,PARENTE PEREIRA PURI, ANA CATARINA,BEATSON, RICHARD ESMOND
申请号：
CA2969783
公开号：
CA2969783A1
申请日:
2015.12.04
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A method for expanding a population of ?d T-cells is provided in which isolated activated Peripheral Blood Mononuclear Cells (PBMCs) are cultured in a medium comprising transforming growth factor beta (TGF-ß) under conditions in which the production of effector ?d T-cells having therapeutic activity against malignant disease is favored. The use of TGF-ß in the production of effector cells in particular V?9Vd2 T-cells is also described and claimed.
