John MAHER,Ana Catarina PARENTE PEREIRA PURI,Richard Esmond BEATSON
申请号：
US15532921
公开号：
US20170342381A1
申请日:
2015.12.04
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A method for expanding a population of γδ T-cells is provided in which isolated activated Peripheral Blood Mononuclear Cells (PBMCs) are cultured in a medium comprising transforming growth factor beta (TGF-β) under conditions in which the production of effector γδ T-cells having therapeutic activity against malignant disease is favored. The use of TGF-β in the production of effector cells in particular Vγ9Vδ2 T-cells is also described and claimed.
