MAHER, John,BEATSON, Richard Esmond,PARENTE PEREIRA PURI, Ana Catarina
申请号：
DK15819849
公开号：
DK3227435T3
申请日:
2015.12.04
申请国别(地区):
DK
年份:
2020
代理人:
摘要：
A method for expanding a population of γδ T-cells is provided in which isolated activated Peripheral Blood Mononuclear Cells (PBMCs) are cultured in a medium comprising transforming growth factor beta (TGF-β) under conditions in which the production of effector γδ T-cells having therapeutic activity against malignant disease is favored. The use of TGF-β in the production of effector cells in particular Vγ9Vδ2 T-cells is also described and claimed.
