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CONTROLLING THE ACTIVITY OF GROWTH FACTORS, PARTICULARLY TGF-BETA, IN VIVO
专利权人:
发明人:
Adam Monsalve,Jon P. Dobson
申请号:
US14261586
公开号:
US20150306220A1
申请日:
2014.04.25
申请国别(地区):
US
年份:
2015
代理人:
摘要:
TGF-β growth factor and its latent complex are conjugated to magnetic micro- or nanoparticles and to magnetic micro- or nanodiscs. By exposing the resulting conjugates to magnetic fields, the TGF-β growth factor can be released from its latent complex in vivo, potentially making it useful in tissue engineering and regenerative medicine. And by exposing a conjugate of TGF-β growth factor and a magnetic particle to a sufficiently strong, radiofrequency magnetic field, the TGF-β growth factor can be denatured and thereby deactivated, potentially making it possible to avoid triggering tumorigenesis, atherosclerosis, fibrotic disease, and cancer.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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