COOK, BRIAN NICHOLAS,HARCKEN, CHRISTIAN,LEE, THOMAS WAI-HO,LIU, PINGRONG,MAO, CAN,LORD, JOHN,MAO, WANG,RAUDENBUSH, BRIAN CHRISTOPHER,RAZAVI, HOSSEIN,SARKO, CHRISTOPHER RONALD,SWINAMER, ALAN DAVID
申请号：
CA2722811
公开号：
CA2722811C
申请日:
2009.05.01
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Disclosed are compounds of the formula I which block the interaction of CCR1and its ligands and are thus usefulfor treating a variety of diseases and disorders that are mediated orsustained through the activity of CCR1 including autoimmunediseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosedare pharmaceutical compositions comprising thesecompounds, methods of using these compounds in the treatment of variousdiseases and disorders, processes for preparing thesecompounds and intermediates useful in these processes.
