Can Mao;David Smith Thomson;Alan David Swinamer;Daniel Kuzmich
发明人:
Daniel Kuzmich,Can Mao,Alan David Swinamer,David Smith Thomson
申请号:
US13184855
公开号:
US08263597B2
申请日:
2011.07.18
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed indazoles compounds that are useful as antagonists of CCR1 activity and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.