DISALVO, DARREN,KUZMICH, DANIEL,MAO, CAN,RAZAVI, HOSSEIN,SARKO, CHRISTOPHER,SWINAMER, ALAN DAVID,THOMSON, DAVID,ZHANG, QIANG
申请号:
CA2722923
公开号:
CA2722923C
申请日:
2009.04.23
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Disclosed indazoles compounds that are useful as antagonists of CCR1 activityand are thus useful for treating avariety of diseases and disorders that are mediated or sustained through theactivity of CCR1 including autoimmune diseases, suchas rheumatoid arthritis and multiple sclerosis. Also disclosed arepharmaceutical compositions comprising these compounds,methods of using these compounds in the treatment of various diseases anddisorders, processes for preparing these compoundsand intermediates useful in these processes.