КХИМ Че Хак (KR),НАМ Кхюн Ван (KR),ПАРК Со Хун (KR),КХИМ Чу Вон (KR),КХИМ Сан Ёп (KR)
申请号：
RU2015102553
公开号：
RU2015102553A
申请日:
2013.04.30
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. A pharmaceutical composition comprising: fimasartan, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof hydrochlorothiazide, pharmaceutically acceptable salt, a hydrate thereof or a solvate thereof isvyazuyuschee substance having a viscosity of 20 mPa · s to 1,000 mPa · s at 25 ° C.2. A pharmaceutical composition according to claim 1, wherein the binder comprises at least one selected from the group consisting of hydroxypropylcellulose, hydroxypropylmethylcellulose and polivinilpirrolidon.3. A pharmaceutical composition according to claim 1, wherein the pharmaceutical composition has a relative standard deviation (RSD), is 4.0% or less, in the test for uniformity soderzhaniya.4. A pharmaceutical composition according to claim 1, wherein the pharmaceutical composition is in the form tabletki.5. A pharmaceutical composition according to claim 4, wherein the tablet comprises a non-coated tablet and a layer pokrytiya.6. The pharmaceutical composition of claim 5 wherein the uncoated tablet has a crush strength was 7 kP or bolee.7. A pharmaceutical composition according to claim 1, wherein the pharmaceutical composition is for treatment gipertenzii.8. A process for preparing a pharmaceutical composition comprising fimasartan, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof and hydrochlorothiazide, pharmaceutically acceptable salt, a hydrate thereof or a solvate thereof, the method comprising the steps of: forming a mixture comprising fimasartan, a pharmaceutically acceptable salt thereof, a hydrate or solvate thereof and hydrochlorothiazide, pharmaceutically acceptable salt, a hydrate thereof or a solvate thereof, obtaining the granules by mixing the mixture with a binder solution in which a binder is dissolved substance having1. Фармацевтическая композиция, содержащая:фимасартан, его фармацевтически приемлемую соль, его гидрат или его сольватгидрохлортиазид, его фармацевтически приемлемую соль, его гид
