PURPOSE: A hypoglycemic composition containing an onion skin extract is provided to suppress the increase of blood glucose after eating a meal and to reduce side effects such as abdominal distention and diarrhea caused by abnormal fermentation of starch ingredients in large intestine.CONSTITUTION: A method for preparing an onion skin extract which enhances the content of quercetin and phenolic ingredients comprises the steps of: drying and pulverizing prepared onion skin mixing the pulverized onion skin with ethyl alcohol or organic acid and stirring the mixture at 25-50°C for 30 minutes to 12 hours and filtering and freeze-drying the reacted liquid. A hypoglycemic composition contains the onion skin extract as an active ingredient.COPYRIGHT KIPO 2013[Reference numerals] (AA) Inhibiting activity (%) (BB) Alpha-glucosidase inhibiting activity (CC) Alpha-amylase inhibiting activity (DD) Concentration of onion skin extract본 발명은 양파껍질 추출물을 함유하는 혈당강하제 조성물을 제공한다. 본 발명의 양파껍질 추출물을 함유하는 혈당강하제 조성물은 α-글루코시다아제(α-glucosidase)의 활성은 강력하게 저해하면서도 α-아밀라아제(α-amylase)의 활성은 약하게 저해함으로써 식후 혈당상승은 억제하면서도 대장 내에서의 전분 성분의 비정상적인 발효로 인한 복부팽만, 설사 등의 부작용은 경감시키는 효능을 나타낸다.
