Jan Tavernier,Lennart Zabeau,Gilles Uze,Franciane Paul,Yann Bordat,Genevieve Garcin
申请号：
US14905348
公开号：
US09732135B2
申请日:
2014.07.01
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to a fusion protein, comprising a cytokine antagonist and a targeting moiety, preferably an antibody or anti-body like molecule. In a preferred embodiment, the cytokine antagonist is a modified cytokine which binds to the receptor, but doesnt induce the receptor signalling. The invention relates further to a fusion protein according to the invention for use in treatment of cancer and immune- or inflammation-related disorders.
