TARGETING OF CYTOKINE ANTAGONISTS

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专利权人:

发明人:

TAVERNIER JAN,ZABEAU LENNART,UZ‰ GILLES,PAUL FRANCIANE,BORDAT YANN,GARCIN GENEVI¨VE

申请号：

IN201627000823

公开号：

IN201627000823A

申请日:

2016.01.08

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

The present invention relates to a fusion protein comprising a cytokine antagonist and a targeting moiety preferably an antibody or anti body like molecule. In a preferred embodiment the cytokine antagonist is a modified cytokine which binds to the receptor but doesn t induce the receptor signalling. The invention relates further to a fusion protein according to the invention for use in treatment of cancer and immune or inflammation related disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/