Thomas Waldmann;Bibiana Bielekova;Roland Martin;Henry McFarland
发明人:
Roland Martin,Henry McFarland,Bibiana Bielekova,Thomas Waldmann
申请号：
US12401543
公开号：
US08298525B2
申请日:
2009.03.10
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed is a method of administering an interleukin-2 receptor (IL-2R) antagonist to a subject to treat an autoimmune disease. In particular embodiments, the IL-2R antagonist is an anti-IL-2R monoclonal antibody specific for one or more chains of the IL-2R, such as the alpha-chain, for example daclizumab. In other particular embodiments the autoimmune disease is multiple sclerosis. In certain embodiments administration of interferon-beta is combined with administration of an antagonist of the IL-2R to provide significant clinical improvement in a subject with an autoimmune disease.
