Chanel Parfums Beauté;Kyushu University, National University Corporation
发明人:
申请号：
EP18785558.0
公开号：
EP3691606A1
申请日:
2018.10.05
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention provides a method for producing a nonaqueous composition for external use on the skin comprising a strongly hydrophilic amphiphilic solid active ingredient solubilized in an oil phase. The present invention relates to a method for producing a nonaqueous composition for external use on the skin comprising a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed in an oil phase, the method comprising the steps of: dissolving a surfactant in an oil phase to obtain a surfactant solution； mixing the obtained surfactant solution with a strongly hydrophilic amphiphilic solid active ingredient to obtain a suspension； and allowing the obtained suspension to stand still to obtain a transparent composition. According to the method of the present invention, unlike conventional methods for preparing S/O formulations, the strongly hydrophilic amphiphilic solid active ingredient can be solubilized in an oil phase without the process of emulsification and freeze drying.
