您的位置: 首页 > 农业专利 > 详情页

Pyrrolopyridinone derivatives as TTX-S blockers
专利权人:
RaQualia Pharma Inc
发明人:
KAWAMURA, Kiyoshi,MORITA, Mikio,YAMAGISHI, Tatsuya
申请号:
ES13782571
公开号:
ES2645984T3
申请日:
2013.04.25
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
A compound of the following formula (I): ** Formula ** in which: A is a mono or bi-carbocyclic or mono or bi-heterocyclic ring that may contain from 0 to 4 heteroatoms selected from O, N and S; B is -NR2- or - (C>; = O) -; C is - (C>; = O) - or -NR2-; R1 is independently selected from the group consisting of; (1) hydrogen, (2) -On-C 1-6 alkyl where the alkyl is unsubstituted or substituted with one or more substituents independently selected from R 11, (3) -C 3-7 cycloalkyl where the cycloalkyl is unsubstituted or substituted with one or more substituents independently selected from R11, (4) -On-aryl where the aryl is unsubstituted or substituted with one or more substituents independently selected from R11, (5) -S-C1-6 alkyl, where the alkyl is unsubstituted or substituted with one or more substituents independently selected from R11, (6) -S-aryl where the aryl is unsubstituted or substituted with one or more substituents independently selected from R11; (7) -NH-C1-6 alkyl, where the alkyl is unsubstituted or substituted with one or more substituents independently selected from R11 and (8) -NH-aryl, where the aryl is unsubstituted or substituted with one or more substituents independently selected from R11; R2 is independently selected from the group consisting of: (1) hydrogen, (2) halogen selected from chlorine, bromine and fluorine, (3) hydroxyl, (4) -On-C1-6 alkyl, where the alkyl is unsubstituted or substituted with one or more substituents independently selected from R7, (5) -On C3-6 cycloalkyl, where the cycloalkyl is unsubstituted or substituted with one or more substituents independently selected from R7, (6) -On-C2 alkenyl- 4, where the alkenyl is unsubstituted or substituted with one or more substituents independently selected from R7, (7) -On-phenyl or -Onnaphthyl, where the phenyl or naphthyl is unsubstituted or substituted with one or more substituents independently selected from R7 , (8) -On-heterocyclyl, where the heterocyclyl is unsubstituted o
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充