您的位置: 首页 > 农业专利 > 详情页

СУЛЬФОНАМІДНІ ПОХІДНІ БЕНЗИЛАМІНУ ДЛЯ ЛІКУВАННЯ ЗАХВОРЮВАНЬ ЦЕНТРАЛЬНОЇ НЕРВОВОЇ СИСТЕМИ (ЦНС)
专利权人:
ADAMED SP. Z O.O.
发明人:
Kolaczkowski, Marcin,Колачковскі Марцін,Marcinkowska, Monika,Марцінковска Моніка,Bucki, Adam,Буцкі Адам,Lysakowski, Tomasz,Лизаковскі Томаш,Pawlowski, Maciej,Павловскі Мацєй
申请号:
UA201411311
公开号:
UA112109C2
申请日:
2013.03.20
申请国别(地区):
UA
年份:
2016
代理人:
摘要:
Sulphonamide derivatives of benzylamine of formula (I), wherein A represents phenyl unsubstituted or substitutedor 9- or 10-membered bicyelic group, linked to -(O)x -(СH2)y-through one of its aromatic carbon atoms, consisting of benzene ring fused with -membered heteroaromatic ring containing 1 or 2 heteroatoms independently selected from the group consisting of N and O, wherein such bicyclic group is unsubstituted or substituted or with 5- or 6-meinbered non-aromaticheterocyclic ring having 1 or 2 О atoms, wherein heterocyclic ring is unsubstituted or substituted with one or more C1-C3-alkyls D represents a group selected from: phenyl unsubstituted or substituted naphthyl unsubstituted or substituted thiophene unsubstituted or substituted bicyclic group consisting of imidazolering fused with 5-membered non-aromatic carbocyclic ring bicyclic group consisting of benzene ring fused with 5-membered heteroaromatic ring, having 1 or 2 heteroaloms independently selected from the group consisting of N, O and S, unsubstituted or substituted and linked to sulphonamide moiety through one of carbon atoms of benzene ring and bicyclic group consisting of benzene ring fused with -or 6-membered non-aromatic heterocyclic ring having 1 or 2 heteroatoms independently selected from the group consisting of N and O, unsubstituted or substituted, and linked to sulphonamide moiety through one of carbon atoms of benzene ring R represents H or CH 3 x is 0 or 1 yis 2 or 3 and pharmaceutically acceptable salts and solvates thereof, with the provisos that if x is 0 and у is 2, then D is naphthyl unsubstituted or substituted with one halogen atom, and if R represents СH 3, then A is not unsubstituted or substituted phenyl. The compounds can be used in the treatment and/or prophylaxis of central nervous system disorders.Сульфонамідні похідні бензиламіну загальної формули (І): EMBED ISISServer (I), де А являє собою: феніл, не заміщений або заміщений одним замісником, вибраним з групи, до складу я
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充