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COMPOSITION MULTIPARTICULAIRE, REVÊTUE, ENTÉRIQUE, À LIBÉRATION CONTRÔLÉE D'HUILE DE MENTHE POIVRÉE ET PROCÉDÉS ASSOCIÉS
专利权人:
ZX PHARMA; LLC
发明人:
SHAH, SYED,HASSAN, DANIEL,HASSAN, FRED
申请号:
EP13883071
公开号:
EP2872123A4
申请日:
2013.09.23
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
A method of making an L-menthol dosage form includes forming a wet granulation including an L-menthol source and at least one pharmaceutical excipient. The wet granulation is extruded into an extrudate and the extrudate is cut into individual core pieces. The individual core pieces are spheronized into individual spheronized cores and the individual spheronized cores are dried to form dried individual spheronized cores. The dried individual spheronized cores are spray coated with a liquid proteinaceous material that forms a film of a proteinaceous material over the dried individual spheronized cores. The film of proteinaceous material is dried over the dried individual spheronized cores to form individual subcoated cores. An enteric coating is applied and dried over the individual subcoated cores to form a plurality of individual enteric coated cores.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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