Glycosaminoglycan-antagonising fusion proteins and methods of using same

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专利权人:

ANTAGONIS BIOTHERAPEUTICS GMBH

发明人:

Andreas Kungl

申请号：

US15113394

公开号：

US10047133B2

申请日:

2015.01.22

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to novel monomeric fusion proteins derived from human GAG binding proteins such as chemokines with increased glycosaminoglycan (GAG) binding affinity and knocked-out or reduced GPCR activity compared to wild type GAG binding proteins, which are highly selectively competitive and are of increased bioavailability, and to their use for prevention or treatment of pathological cell movement as in metastasis.

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中国工程科技知识中心

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