Variable domains of immunoglobulin anti-TNFR1 (type 1 or P55 receiver), including at least 95% amino acid sequences identical to DOM1H-574-188 sequences, (b) Multi-characteristic combination； TNFR1 antibiotics and their anti-inflammatory use.
DE SILVA, INUSHA,SEPP, ARMIN,STOOP, ADRIAAN ALLART.
申请号：
CL2012001055
公开号：
CL2012001055A1
申请日:
2012.04.25
申请国别(地区):
CL
年份:
2012
代理人:
摘要：
Anti TNFR1 immunoglobulin variable domain (TNF Receptor Type 1 or p55) Amino Acid Sequence comprising at least 95% identical to the sequences of dom1h - 574 - 188.And dom1h - 574 - 214； Nucleic Acid, Vector and host cell that ligand encoding； Parallel； antagonist of TNFR1 and anti-inflammatory use.Dominio variable de inmunoglobina anti-TNFR1 (receptor TNF alfa tipo 1 o P55) que comprende secuencia aminoacídica al menos un 95% identica a las secuencias de DOM1H-574-188, ... y DOM1H-574-214； ácido nucleico, vector y célula huésped que lo codifican； ligando multiespecífico； antagonista de TNFR1 y su uso antiinflamatorio.
